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T6037 |
E-64
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Proteinase inhibitor E 64,E 64,E64 |
Cysteine Protease
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Antibacterial
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Autophagy
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E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM. |
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T6573 |
E 64c
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NSC 694279,EP 475,Loxistatin Acid |
SARS-CoV
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Cysteine Protease
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E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor. |
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T11888 |
LtaS-IN-1
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Others
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Antibacterial
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T82834 |
Bombinin-BO1
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Bombinin-BO1, an antimicrobial peptide from the skin secretions of the Bombina orientalis toad, exhibits activity against E. coli, S. aureus, and Candida albicans with minimum inhibitory concentration (MIC) values of 64,... |
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T38259 |
Phenelfamycin E
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Phenelfamycin E is an antibiotic originally isolated from Streptomyces. It is active against β-hemolytic Streptoccus, S. pneumoniae, C. difficile, C. perfringens, and P. magnus128 μg/ml). Phenelfamycin E (4-64 mg/kg) inc... |
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T38917 |
Antibacterial agent 50
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Antibacterial agent 50 (example 47) is a compound that exhibits antibacterial activity. It shows minimum inhibitory concentration (MIC) values of 32, 64, and 128 mcg/mL against three strains of E. coli, namely NCTC 13351... |
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T78673 |
Antibacterial agent 135
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Antibacterial Agent 135 (example 7) effectively inhibits various bacteria, including P. aeruginosa, A. baumannii, E. coli, and K. pneumoniae, with a minimum inhibitory concentration (MIC) greater than 64 μg/mL [1]. |
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T39790 |
LpxC-IN-5
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LpxC-IN-5 is a potent, non-hydroxamate inhibitor of LpxC, which is an enzyme known as UDP-3-O-acyl-N-acetylglucosamine deacetylase. It exhibits an IC50 value of 20 nM. Furthermore, LpxC-IN-5 displays antibacterial activi... |
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T36746 |
Leoidin
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Leoidin is a depsidone originally isolated from L. gangaleoides that has antibacterial and enzyme inhibitory activities.1,2,3 It is active against the bacteria E. faecalis, H. influenzae, M. catarrhalis, S. aureus, and S... |
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T83705 |
BING TFA
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Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria |
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BING, a antimicrobial peptide discovered in Japanese medaka fish (O. laptipes), originates from vacuolar protein sorting-associated protein 13D-like (Vps13D). It exhibits efficacy against a range of Gram-negative and Gra... |
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T37874 |
Feglymycin
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Feglymycin is a 13-amino acid peptide originally isolated from Streptomyces that has antibacterial and antiviral activities. It is active against Gram-positive bacteria (MICs = 32-64 μg/ml) and inhibits HIV viral replica... |
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T38382 |
8Br-HA
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8Br-HA is an inhibitor of fragile histidine triad diadenosine triphosphatase (FHIT; IC50= 0.12 μM).1It inhibits the growth of HCC827 and H460 lung cancer cells (GI50s = 0.87 and 5.9 μM, respectively).
1.Kawaguchi, M., Se... |
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T36110 |
L-Pyrohomoglutamic Acid
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L-Pyrohomoglutamic acid is an amino acid building block.1,2It has been used in the synthesis of ligands for FK506-binding proteins (FKBPs) and histone deacetylase (HDAC) inhibitors.
1.Pomplun, S., Wang, Y., Kirschner, A.... |
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T36649 |
AN3661
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AN3661, a potent antimalarial lead compound, targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue subunit 3 (PfCPSF3). AN3661 inhibits Plasmodium falciparum laboratory-adapted strains... |
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T35683 |
2-deoxy-D-Glucose-13C6
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2-deoxy-D-Glucose-13C6 |
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2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits h... |
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T35881 |
Resolvin E2
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Resolvin E2 (RvE2) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acidviaan 18-HEPE intermediate, which is formed by aspirin-acetylated COX-2-... |
